The micro compression cell is a simple device to allow for the squeezing of a soft solid or semi-liquid sample between two circular windows prior to analysis via transmission spectroscopy. The windows of choice from NaCl, KBr, CaF₂, BaF₂ or ZnSe options are held within a holder that in turn mounts into the sampling compartment of any spectrometer via a standard 3” x 2” slide mount fixing. After positioning of the windows and the sample within the holder, the windows are compressed together by tightening of a front cap. The design of this front cap allows for its rotation but the windows do not rotate in relation to each other. Hence there is minimal possibility of the sample placed between the windows being disturbed from this rotational movement when tightening the cap. The clear aperture of 7.0 mm allows for a good signal when placed at the sampling focus of an FTIR spectrophotometer using a standard DTGS detector. The overall performance of the cell is subject to the window materials that can be used within this cell. The micro compression cell can also be used with Infrared Microscopes, where the large aperture allows for more than one sample to be loaded at one time.